This recipe creates a rich, velvety cheese sauce using fresh ricotta and cream cheese instead of aged cheeses, making it histamine-safe. The flavor is mild and soothing, perfect for anyone seeking gut-friendly comfort food. With simple ingredients and easy steps, this dish is quick to prepare and kind to your digestion.
Ingredients Needed:
- 2 cups uncooked elbow macaroni: choose white rice or gluten-free pasta if preferred.
- 2 tablespoons butter: unsalted, fresh.
- 2 tablespoons all-purpose flour: or gluten-free flour blend.
- ½ teaspoon salt: optional.
- 1 tablespoon chopped chives: fresh, mild flavor.
- 2 cups fresh milk: whole or lactose-free.
- 1 cup fresh ricotta cheese: smooth and creamy.
- 1 cup cream cheese: softened.
- ¼ cup chopped fresh basil: optional garnish.
How To Make Low Histamine Macaroni and Cheese:
Cook Pasta: Boil macaroni according to package directions. Drain and set aside.
Make Sauce Base: In a skillet over medium heat, melt butter. Whisk in flour and salt. Cook for 2–3 minutes until lightly golden.
Add Milk: Slowly whisk in milk, stirring until mixture thickens and just starts to bubble.
Add Cheese: Remove from heat. Stir in ricotta and cream cheese until smooth.
Combine Pasta & Sauce: Add cooked macaroni to the sauce. Stir gently to coat.
Serve: Sprinkle with chives or basil if desired. Serve immediately.

Recipe Tips:
- Use fresh dairy to keep histamine levels low.
- Eat immediately after cooking to avoid histamine buildup.
- Store leftovers in the fridge within 30 minutes.
- For extra creaminess, blend the sauce before adding pasta.
- Avoid reheating multiple times—histamine levels rise with each cycle.
How to Store & Reheat:
- Room Temperature: Eat within 1 hour.
- Fridge: Store in airtight container up to 24 hours.
- Freezer: Not recommended for low histamine diet due to texture changes and histamine risk. Reheat gently on the stove with a splash of milk.
Nutrition Facts (per serving):
- Calories: ~320
- Sodium: ~290 mg
- Protein: ~12 g
- Fat: ~14 g
- Carbs: ~38 g
- Fibre: ~2 g
- Sugar: ~4 g
FAQs:
1. Can I use dairy-free cheese for low histamine mac and cheese?
Yes, if it’s made from fresh ingredients and is not fermented or aged. Check labels for additives.
2. Is basil safe for histamine intolerance?
Most people tolerate fresh basil well, but you can omit it if you’re sensitive.
3. Can I make this ahead of time?
It’s best eaten fresh. If you need to prep ahead, cook pasta and store separately, then make the sauce fresh before serving.
4. Which pasta is best for low histamine diets?
Freshly cooked white rice pasta or plain wheat pasta is fine for most. Avoid long storage after cooking.
5. How can I thicken the sauce without flour?
Use cornstarch or arrowroot mixed with cold milk, then heat until thick.
Try More Recipes:
Low Histamine Macaroni And Cheese
Course: DinnerCuisine: AmericanDifficulty: Easy4
servings10
minutes15
minutes320
kcalA creamy, mild, and gut-friendly twist on classic mac and cheese using fresh ricotta and cream cheese instead of aged cheese.
Ingredients
2 cups uncooked elbow macaroni
2 tbsp butter
2 tbsp all-purpose flour
½ tsp salt (optional)
1 tbsp chopped chives
2 cups milk
1 cup fresh ricotta cheese
1 cup cream cheese
¼ cup chopped basil (optional)
Directions
- Boil pasta, drain, set aside.
- Melt butter, whisk in flour and salt, cook 2–3 min.
- Add milk slowly, whisk until thickened.
- Remove from heat, stir in ricotta and cream cheese until smooth.
- Mix pasta with sauce, garnish with chives or basil. Serve hot.
